Clinician Resources
Cautious, Evidence-Based Opioid Prescribing
The clinical evidence for efficacy and safety of long-term opioid use for chronic, noncancer pain is limited. However, evidence for large increases in opioid prescribing for such conditions and simultaneously, rapid increases in opioid-related adverse events and deaths as well as increases in addiction and diversion have an ever-growing evidence base. “Cautious, Evidence-Based Opioid Prescribing” is a review on this subject from Physicians for Responsible Opioid Prescribing. This is a succinct and well-referenced document that all clinicians who prescribe opioids should be familiar with; therefore we have included it on the Prescribers’ Clinical Support System for Opioid Therapies website.
Elinore McCance-Katz, MD, PhD
Medical Director
PCSS-M Clinical Guidances
- Methadone and Drug Interactions
- Methadone Diversion Minimizing the Risk in Office-based Practices
- Methadone Dosing for Pain and Equi-analgesic Tables
- Methadone Induction Dosing for Chronic Non-cancer Pain in Opioid Naïve Patients
- Pharmacology, Pharmacokinetic and Pharmacodynamic Properties of Methadone
- Opioid Treatment Program Methadone Induction Dosing








